If you are over 50 you should read this post. It contains important updates for you and your partner about developments in longevity research during 2015.
One of my main objectives for the Design Your New Life Website is to keep you updated on progress in the exciting field of longevity and life extension science and medicine.
There is a general lack of awareness of what is happening and the potential implications for humanity, and us individually.
I have made it my mission to get the message out there to as many people over as possible because they need to know so that there are specific actions they should be taking right now to ensure that they are in the best possible position to benefit from longevity treatments and medicines as they become generally available.
There are also wider implications to consider; not least with the prospect of a longer healthier life, will their social security (pensions or superannuation, depending which country they live in) be sufficient to ensure that they are able to maintain their current quality of life during their retirement years.
So, as you will know if you have read my articles, I was very excited with the real progress in Life Extension technology and medicine during 2015 . I have published a number of articles keeping you up-to-date with the most exciting developments (I picked 3 of my favourites to include in this update, along with comments and updates from some of the most respected experts in the field of longevity and life extension).
The other huge issue is the economic implications of life extension and the increasing number of older people as a percentage of the population, which has every government in the developed world concerned about how they will fund their ongoing social security programs.
But they do not really understand or appreciate the incredible positive impact that life extension technology could have, that would make their concerns irrelevant.
Be sure to read my conclusions at the end of this article to see the staggering cost burden Cancer and Heart disease treatment and care are placing on social security systems, that longevity treatments and medicine could potentially reduce to an insignificant level.
I have not gone into detail on all of the initiatives currently being researched and trialed around the world, because:
a) there are too many to include in a single update,and
b) much of the language and terminology is not easy to translate into every day English.
But I have included links to the expert updates for those of you who would like to delve more deeply, and I will be focusing on keeping you up-to-date regularly on an ongoing basis as significant material becomes available.
What the Experts Are Saying
I have chosen 3 expert articles to bring to your attention because they were written by acknowledged industry leading organisations and individuals:
1. Age Reversal Goes Live in 2015
In a cover article in the highly respected “Life Extension Magazine”, William (Bill) Faloon, co-founder and Director of the “Life Extension Foundation” a non-profit organisation formed in 1980, whose long-term goal is the radical extension of the human lifespan wrote:
“For the first time, therapies to induce meaningful age reversal are being transformed into aggressive human research initiatives.
To put this into perspective, I have attended anti-aging scientific conferences since 1978. The focus was on disease prevention and slowing aging.
The concept of systemic age reversal was discussed as a breakthrough that would occur “sometime in the future.
That “future” arrived in 2015.
Scientists are now pushing through human studies with the objective of biologically transforming old people into measurably younger individuals.
The motives of these scientists go beyond profit and intellectual curiosity. These experts firmly believe that many aspects of pathologic aging can be eradicated using novel approaches that are being incorporated into human clinical trials.
The fact we may be so close to demonstrating systemic age reversal makes it imperative that we remain healthy enough to benefit.”
2. A Look Back at 2015 in Longevity Science
In an article in January 2016 titled A Look Back at 2015 in Longevity Science, Fight Aging.Org expressed it’s opinion that in years to come, we’ll consider 2015 to be the point at which things really started to move for SENS.
According to The SENS Foundation
“SENS is an acronym that stands for Strategies for Engineered Negligible Senescence.
The Strategies for Engineered Negligible Senescence, then, amount to a flexible way of approaching the development and continuous improvement of rejuvenation biotechnologies, to combat age-related disease and frailty however it may manifest itself now and tomorrow.”
If you want to find out more about SENS and senescence, follow the link in the “references” section at the end of this article.
3. Great Year for Longevity
In an article titled “Great Year for Longevity” published on 29 December 2015 by the Chairman of the “Maximum Life Foundation” David Kekich, he comments in his introduction:
“I usually hate seeing another year go by, especially with advancing age. 2015 was different though. So many longevity advancements can’t help but stir your optimism.
An approved clinical trial for longevity? Whoever thought it would happen this soon?
On June 24th, researchers met with regulators from the US Food and Drug Administration (FDA) to make the case for a clinical trial designed to show the validity of the approach.”
These 3 organisations are among the most highly respected and leading authorities in the field of life extension.
To read these comments from them confirms my own feeling that the developments in Life extension during 2015 gathered momentum at a rapid pace. I am hopeful that this may be the start of a period of rapid development that will see treatments and medicines generally available in the not-too-distant future.
This will depend, to an extent, on the co-operation of the FDA, and a positive change has occurred in 2015 in terms of their approval for clinical trials, effectively an acknowledgement that there is merit in further research.
These comments by Dr Robert Temple, deputy director of the FDA about the clinical trials were especially encouraging
“Their hope is that a wide variety of age related problems, loss of muscle tone, dizziness, falls, dementia, loss of eyesight, all of those things” (could be eliminated).
“That would be something never done before. If you really are doing something to alter ageing the population of interest is everybody. It surely would be revolutionary if they can bring it off.”
In the next section I have provided an overview of the 3 most important articles on life extension that I published during 2015.
My Most Significant Posts on Life Extension Breakthroughs in 2015
To read the full articles just click on the titles.
In his weekly Longevity News Alert on 6th October 2015, leading longevity advocate David Kekich summarised the key findings of a new article released by leading U.S. Gene Therapy research company Bioviva which announced that it had become the first company to treat a person with gene therapy to reverse biological aging.
BioViva CEO Elizabeth Parrish confirmed that “the subject is doing well and has resumed regular activities. Preliminary results will be evaluated at 5 and 8 months with full outcome expected at 12 months.”
She added that “Gene therapy allows doctors to treat disease at the cellular level by inserting a gene into a patient’s cells instead of using the regular modalities of oral drugs or surgery.
Although not generally considered a disease, cellular aging is the leading cause of death in the developed world, and the aging cell is also responsible for the diseases of aging, including Alzheimer’s disease, heart disease and cancer.”
In a news update on 5th December 2015 William (Bill) Faloon, co-founder and Director of the “Life Extension Foundation” a non-profit organisation formed in 1980, whose long-term goal is the radical extension of the human lifespan, published details and news reports of the US Federal Drug Administration’s (FDA) approval of a large-scale to see if Metformin ( a drug that has been used worldwide since its introduction in the UK in 1957 to treat type II diabetes) can protect against the multiple diseases of human aging.
What is most significant about this announcement (besides the drug’s incredible potential implications for the future of humanity) and has caught the attention of the words media, is that it is the first time ever that the FDA has authorised any human trials on a drug with a view to establishing its potential to protect against the multiple diseases of human aging.
In an exciting research breakthrough in human cell therapy a team from the University of Queensland has created a mini kidney from a patients skin cells.
The news release, announced that one of their research teams had created a live mini-kidney formed in a dish from human induced pluripotent stem cells which were created from a patients skin cells (my note: Pluripotent stem cells are master cells able to make cells from all basic body layers, so they can potentially produce any cell or tissue the body needs to repair itself. Like all stem cells, pluripotent stem cells are able to self-renew, meaning they can perpetually create more copies of themselves)
I hope I have provided enough information to give you a sense of the progress being made? In the references section below I have included links to all the published articles mentioned in this post.
An important point to note that I briefly mentioned in my introduction, is that the US Government is spending about $12 billion annually on research into diseases associated with aging, but only $2 billion of that on aging itself.
It seems farcical to me that the focus is on “effects” rather than the “cause”, but hardly surprising as Heart disease and cancer alone accounted for 65% of all deaths in the US in 2010.
This $12 billion is just the investment in research, and is a drop in the ocean compared to the cost to treat and care for people with cancer and heart disease.
According to CDC (Centre for Disease Control and Prevention):
“Eighty-six percent of all health care spending in 2010 was for people with one or more chronic medical conditions.
Cancer care cost $157 billion in 2010 dollars.
The total costs of heart disease and stroke in 2010 were estimated to be $315.4 billion.”
That’s a staggering $472.4 billion. Just imagine the impact on the US economy if a refocus on treating the causes of aging produced positive results that could be made generally available in the next 5 years, and which could dramatically reduce the number of people contracting and dying from these age related diseases (you and I possibly included). The pressure on the social security systems in all developed nations would be dramatically reduced.
But that’s not all. If the older people no longer contracting these diseases were still earning money in their retirement, that would further reduce the burden on the social security system.
I personally believe it’s a matter of when rather than whether that happens. For the sake of all of us, lets hope it doesn’t take too long.
In my next article on the subject of life extension I ask the question: “Is aging a disease?” This question has been widely debated in the medical community and has potentially major consequences for the future development of life extension treatments and medicines.
Copyright © 2015 designyournewlife.com
a division of DA Web Enterprises Pty Ltd
CDC Cost of Diseases of Aging http://www.cdc.gov/chronicdisease/overview/
A Look Back at 2015 in Longevity Science – Fight Aging.org
Great Year for Longevity- Maximum life Foundation. http://maxlife.org/
Age Reversal Goes Live in 2015
What Does SENS Stand For?